The official "standard" setting for D&D. Most adventures exist in this setting.
Introduces Steampunk elements: Trains, Airships, Artificers, and Mechanical Contraptions.
[5e Book] Eberron: Rising from the Last War
Wayfinder's Guide to Eberron (5e source material)
Ravenloft & Barovia
Spoooooky. Twilight Zone-esque, official setting for the adventure module Curse of Strahd.
A worldwide cityscape filled with faction intrigue. Setting sourced from Magic: The Gathering
[5e book] Guildmaster's Guide to Ravnica
Ancient Greece-inspired plane, ruled by powerful deities, with powerful artifacts and monsters
[5e book] Mythic Odysseys of Theros
Exandria (Wildemount, Tal'Dorei)
Official campaign setting of Critical Role, created by Matthew Mercer.