The official "standard" setting for D&D. Most adventures exist in this setting.
Introduces Steampunk elements: Trains, Airships, Artificers, and Mechanical Contraptions.
Wayfinder's Guide to Eberron (5e source material)
Eberron: Rising from the Last War (Official 5e Sourcebook)
Ravenloft & Barovia
Spoooooky. Twilight Zone-esque, official setting for Curse of Strahd.
A worldwide cityscape filled with faction intrigue. Setting sourced from Magic: The Gathering
Guildmaster's Guide to Ravnica (5e sourcebook)
Ancient Greece-inspired plane, ruled by powerful deities, with powerful artifacts and monsters